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Unfavorable environmental conditions such as heat, cold, drought, metal/metalloid toxicity, and pathogens enhance production of intra-and inter-cellular levels of reactive oxygen species (ROS) in plants

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Bisabolol: Extracted from chamomile, bisabolol effectively soothes irritation and redness while enhancing the absorption of other active ingredients

To counteract these adverse effects, AAV-mediated SIRT1 overexpression (AAV-SIRT1) has been explored as a therapeutic strategy to restore SIRT1 levels and protect against NIHL.