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Appendices Appendix 1: Literature Search Strategies Literature Search - Vitamin B12 Economic Evidence-Based Analysis Search date: June 3, 2013 Databases searched: OVID MEDLINE, MEDLINE In-Process and Other Non-Indexed Citations, EMBASE

GHK-Cu works through different mechanisms Wnt pathway activation, anti-inflammatory signaling, reduced androgen receptor sensitivity but it doesn't directly block DHT the way finasteride does, and it doesn't open potassium channels like minoxidil
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Oral Supplementation Oral B12 supplements are widely available, but their effectiveness varies
