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Considered together, these data demonstrate that anesthesia-induced DES is associated with oxidative stress and inflammatory response, with the latter being governed mainly by AA and its derivative oxylipins, namely 5-HETE/LTB4 (5-LOX products) and 12-HETE (12-LOX product) as well as COX-dependent prostaglandins (PGD2, PGE2, PGF2)
Both isomers were nonetheless rapidly metabolized and eliminated (6, 8, 11)
The Role of Adjuvant Immunomodulatory Agents for Treatment of Severe Influenza
