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Description
In June 2026, the FDA updated the OTC weight loss drug alli (orlistat) label to include a warning about the rare risk of kidney stones and acute kidney injury

Myers et al., 2013

It involves a period of trial and adjustment

Standard dosing Typical dose: 1 mL per injection Frequency: Once weekly for maintenance, twice weekly for active weight loss Duration: 12-16 weeks initially, with reassessment before continuing Some providers recommend starting with twice-weekly injections during the first 4-8 weeks of a weight loss program, then transitioning to weekly maintenance injections once you've reached your goal weight

Written by Richard Block Richard Block is an editorial jack-of-all-trades at Goldn Connect with Richard Block on LinkedIn
