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It has been shown that exogenous LF is hydrolyzed by proteases and mainly exists in the form of peptides, which have small molecular masses, are well digested and absorbed, and even exhibit higher biological activities (66)

Moreover, only 54% of patients in those economics have access to oral cysteamine therapy, and there is limited access to cysteamine eye drops, supportive therapies, and standard diagnostic and monitoring tools, all of which are essential for the prevention of disease progression and extended lifespan [159]

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These results supported the researchers' hypothesis that Humanin may be negatively correlated to GH and IGF-1 levels and directly correlated to cellular longevity