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[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Okamura M, Inagaki T, Tanaka T, Sakai J

Ipamorelin activates GHSR-1a (ghrelin receptors) via the PLC/IP3 pathway

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In this context, a newly published systematic review including seven clinical trials showed that the application of vitamin B12 supplementation for metformin-treated T2DM patients will be valuable in preventing or treating vitamin B12 deficiency and neuropathy and should be considered during the T2DM management plan[32]