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Under pathological conditions, microgliaas a function of different stimuliare activated to exert neuroprotective effects (M2 phenotype) or to release inflammatory factors and neurotoxic substances (M1 phenotype)

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Immune system modulation shows potential for enhancing immune surveillance and clearing senescent cells, but is in early stages

Furthermore, combined supplementation with vitamin E and -3 PUFAs may be superior to monotherapy, as vitamin E helps prevent the in vivo oxidation of -3 PUFAs, while the two nutrients together may produce a synergistic effect in mitigating inflammation and modulating lipid metabolism (22)

Strengthening immunity : Enhances immune system function and resilience