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2019;9:e12290

Lipopolysaccharide-induced increase in intestinal permeability is mediated by TAK-1 activation of IKK and MLCK/ MYLK gene

Deficiency of B12 can therefore lead to the destruction of the myelin sheaths, triggering a range of sensations: from tingling or numbness, especially in the hands and feet, to chronic pain and irreparable paralysis