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Transcriptional repression of PGC-1 by mutant Huntingtin leads to mitochondrial dysfunction and neurodegeneration
Biochem Biophys Res Commun (2004) 318(3):75663
Hormonal stimuli initiated by food ingestion cause contraction of the muscular wall of the gallbladder, releasing bile salts into the intestine to facilitate digestion of fat
For example, Gilbert syndrome is associated with severe diarrhea and neutropenia in patients who are treated with irinotecan, which is metabolized by UGT1A1
