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The clinical trial participants were on controlled diets

If you follow a vegan diet, lack B12-rich food, or suffer from health conditions like B12 deficiency, which happens when a person cannot absorb it properly, then you may experience b12 deficiency

In the USA, the maximum dosage per day recommended by the manufacturer (MacNeil Consumer Healthcare) was reduced from 4000 mg (eight 500 mg pills) to 3000 mg (six 500 mg pills) in 2011[35]
