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These hydrophobic interactions indicate the strength of nonpolar forces contributing to the binding

Pallard FV, Degan P, dIschia M, Kelly FJ, Zatterale A, Calzone R, Castello G, Fernandez-Delgado R, Dunster C, Lloret A, Manini P, Pisanti MA, Vuttariello E, Pagano G

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Jun 2009

In a Phase II trial in pancreatic cancer patients, oral curcumin was well tolerated and showed some biological activity in a subset of patients, despite low systemic absorption (Dhillon et al., 2008)
