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They are generally not recommended during pregnancy or breastfeeding, for people with a known allergy to any component of the formulation, or for those with certain medical conditions

Exposure to temperatures above 86F (30C) can degrade the medication rapidly, rendering it unusable

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The effect of long-term glycemic control with semaglutide on diabetic retinopathy complications has not been studied

Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy
