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378,379 These metabolic abnormalities contribute to mitochondrial dysfunction

10.3389/fphys.2015.00397 54 FilipekP

Many studies indicate that chronic, low-grade inflammation may be a key factor in developing conditions like heart disease, diabetes, Alzheimers disease, and cancer

Ariel FD, Manavella PA, Dezar CA, Chan RL.The true story of the HD-Zip family.Trends in Plant Science.2007;12(9):419-426 211

Potential for Chronic Pain : With the compromised detoxification and immune response, individuals may experience persistent inflammation and pain, leading to a cycle of increased ibuprofen use and further glutathione depletion