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Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma

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To take advantage of these positive benefits, pharmaceutical drugs have been developed that either limit endogenous GLP-1 degradation by inhibiting dipeptidyl peptidase-4 (DPP-4 inhibitors such as sitagliptin, saxagliptin, linagliptin, and alogliptin) or activate GLP-1 receptors (GLP-1R agonists such as dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide)