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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48

[DOI] [PubMed] [Google Scholar] 33.Hay G, Clausen T, Whitelaw A, Trygg K, Johnston C, Henriksen T, Refsum H

In the future, high-quality research needs to be further carried out to clarify its clinical positioning and safety, so as to promote its rational application in digestive system diseases

Patients report less burning with a subcutaneous administration, which gives it a slight advantage over an intramuscular injection, according to the CDC

They make sense conceptually but need clinical trials to determine safety, dosage, timing and interactions
