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Influence of glucagon on GFR and on urea and electrolyte excretion: direct and indirect effects

Marsova et al

142 Defects in the filaggrin FLG and FLG2 genes, as well as in loricrin and involucrin, are the most common gene mutations associated with AD, resulting in altered envelope and moisturization issues

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The protonated pyridinium nitrogen of the PLP ring serves as a powerful electron sink: it stabilizes the carbanion that develops at the C of the amino acid as each bond around that carbon is cleaved or rearranged