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Description
Continuous, daily usage without breaks is generally not recommended due to the lack of extensive human data and potential risks 1 2
The closest model to human clinical settings (and with the highest clinical relevancy when humans are excluded) is that using primates

All 20 prioritised variants were poorly represented in the GRCh38 reference genome

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They can help you determine the right dose and discuss any interactions the supplement may have with your current medications or health conditions