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It typically presents as macrocytic megaloblastic anemia and neurological impairments, including sensory and motor disfunctions, predominantly in the lower extremities, ataxia, and in more advanced stages cognitive decline progressing to dementia, as well as psychiatric disturbances (Green et al., 2017)
Common Side Effects: Nausea (most common, especially during titration), vomiting, diarrhea, constipation, abdominal pain, dyspepsia
(Fig.1) Click to read: Gene Therapy in -thalassaemia and other haemoglobin disorders
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