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A lab studying repeated signaling effects may split the total daily exposure into separate administrations to better align with the peptides pulse-oriented use pattern

Larazotide acetate (Zonulin Inhibitor AT-1001), which is an 8-mer peptide and tight junctions (TJ) regulator [84], promotes the correct status of tight junction in epithelial cells [85]

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Okada M, Ortiz E, Corzo G, Possani LD

*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers