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L-carnitine and -tocopherol upregulated mitochondrial transport-related and antioxidant defensive system-related gene expression in liver mRNA levels of the L-carnitine transport-related gene OCTN2 were significantly up-regulated in the L-carnitine and -tocopherol groups

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Acetate, pyruvate, and mevalonate were supplemented after dissolving in water

It's well known that individuals with SZ are prone to metabolic irregularities and bioenergetic dysfunction [1, 36]

However, the basis for the increased lactate and pyruvate, in some instances, may relate to non-mitochondrial processes such as glycolysis as is suggested by the absence of increased alanine and TCA intermediates noted in some other biomarker clusters (Figure 5, group 4)