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Phosphorylated perilipin moves away from the surface of lipid droplets, allowing HSL access to the triglycerides stored within

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This method prevents the medication from leaking into the subcutaneous tissue, allows the medication to stay in the muscles, and can minimize irritation

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However, it exhibits low cell membrane permeability and demonstrates substantial toxicity in animal models, thereby constraining its potential application as a therapeutic agent (Zweygarth et al., 1986)