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The following adverse reactions have been reported in male and female adolescents: premature closure of bony epiphyses with termination of growth, and precocious puberty

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7.2 Hepatic toxicity Hepatic dysfunction represents another major adverse effect associated with chronic exposure to supraphysiological androgen levels

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Despite the lack of explanation currently, it is plausible that vitamin B12 affects sleep in distinct ways for both older and younger adults, due to the notable changes in sleep structure with aging