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Besides the FSP1-CoQ pathway, recent evidence has revealed an alternative ferroptosis defense mechanism involving dihydroorotate dehydrogenase (DHODH) and coenzyme Q10

One of its outstanding attributes is its electron-rich nature, which empowers it to function as a nucleophile in organic reactions

doi: 10.1074/jbc.M406487200 25 EbenS

Inhibiting NETs reduces the production of inflammatory cytokines and inflammatory cell infiltration, which in turn slows the progression of NASH

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