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The field shows growing interest in novel delivery systems, including liposomal formulations, sublingual preparations, and buccal absorption methods, attempting to overcome the documented challenges of glutathiones poor gastrointestinal bioavailability

Vahl N, Jorgensen JO, Skjaerbaek C, Veldhuis JD, Orskov H, Christiansen JS

Maintenance of Intracellular Glutathione Cellular Cys content is kept low as it is cytotoxic in high concentrations and, hence, Cys availability occasionally determines the amount of glutathione synthesis

8,9 It is also involved in the reactive oxygen species (ROS) reduction and protects the cell against ROS damage