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At 30 min after isoprenaline 75 mg/kg s.c

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Furthermore, the same experimental setting was applied to the mice used for bile acid measurement with the exception that the fasting time was 12 hours before the 1-hour glucose treatment (6 mice per group)

Concurrently, increased production of ROS exacerbates lipid peroxidation, compromising membrane architecture and promoting myelin degradation
