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We screen for conditions that would make the procedure unsafe: Severe cardiopulmonary issues that increase procedural risk Active implantable pulse generators like pacemakers that could interfere with RF energy Active infection (systemic or localized) Pregnancy safety not established Skeletal immaturity patients under 18 Our commitment to 100% patient satisfaction means never compromising on safety

Apart from directly modulating mitochondrial physiology, -synuclein oligomers also amplify cytosolic peroxide flux resulting in oxidation of glutathiones (Van Laar et al., 2020)

Way it doesn't do it as forcefully or as much, but it still does it so that should that should show us something

Antioxidants 9:852