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This effect on heart rate is an important safety issue that needs special attention in future trials since obese individuals are at increased cardiovascular risk

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NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in all living cells that is essential in key physiological processes in our bodies

The trial will respect all basic ethical principles of autonomy, justice, goodness of intent and absence of malintent according to the standards of good clinical practice enshrined in the Declaration of Helsinki (Seoul, 2008) and the Oviedo Agreement ( Convenio de Oviedo ) (1997)