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External factors such as the acidification and inflammatory of the tumor microenvironment (TME) could also affect cholesterol metabolism

Oxidative Stress in Cognitive and Epigenetic Aging: A Retrospective Glance

[DOI] [PubMed] [Google Scholar] 29.Goldberg E, Eddy EM, Duan C, Odet F

Effects of age, gender, race, comorbid conditions such as diabetes are often not assessed in the literature

This finding further supports the notion that circulating caspase-cleaved CK-18 fragments serve as a valuable diagnostic biomarker for MASH progression
