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However, zinc will inhibit the activity of the enzyme at concentrations of 5 mM or greater, and reagents that react with cysteine (e.g., iodoacetamide) are potent inhibitors of TEV protease

Frataxin is an iron chaperone that drives the assembly of the Fe-S cluster in mitochondria, while it has recently been identified as a key regulator of ferroptosis by modulating mitochondrial iron homeostasis [140]

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Panc-1 cells were human patient-derived pancreatic ductal adenocarcinoma (PDAC) cancer cell line (from ATCC) that carries both oncogenic KRAS and p53 mutations 33

10.1016/S2468-1253(22)00317-X 108 QuinteroP.PizarroM.SolsN.ArabJ