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Creatine pulls water into the muscles, which can increase water retention in muscle tissue and lead to dehydration if fluid intake isnt properly managed

doi: 10.1371/journal.pone.0074398

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Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid

LTE 4 (along with LTC 4 and LTD 4 ) is the slowly reacting substance causing anaphylaxis