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Novoselova Journal: Immunobiology Journal ranking: Q2 Key takeaways: Thymic peptides thymulin and thymopentin significantly reduce disease severity in mice with experimental autoimmune encephalomyelitis, with thymulin showing a longer-lasting effect

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The mevalonate pathway affects the production of CoQ10, an endogenous antioxidant involved in regulating iron metabolism

Strategies to boost host defenses such as increasing glutathione synthesis in macrophages, are also investigated as adjuncts for therapy (Nasiri et al., 2024)

Betaine can effectively delay the progression of fibrosis by downregulating TGF-1, alpha-smooth muscle actin ( -SMA), and collagen type I alpha 1 chain (COL1A1), regulating the balance of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-1/-2, and inhibiting the activation of hepatic stellate cells (23, 125, 134136)