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Dibutyryl-cGMP, a synthetic cGMP derivative, reduces ionomycin-stimulated eryptosis [170]

WT mice were used as controls

DarleyUsmar and coworkers have shown that HNE directly modifies Keap1, which allows Nrf2 to avoid degradation and migrate to the nucleus where it can bind to EpRE elements in the promoters of the human GCLC and GCLM genes (Levonen et al., 2004)

464,465 Furthermore, liposome-encapsulated trans-crocetin (TC) is longer lasting than free TC, with a longer duration of oxygenation in vitro and an extended half-life in vivo in the context of CARDS