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It felt like a small act of resistance in a world wired to optimize every single thing
Biology of MDD: Elevated MAO-A Levels in the Brain While the monoamine theory of depression suggests that monoamine levels are lowered in depression, it does not explain how monoamine lowering takes place.22 Because the enzyme MAO-A metabolizes and regulates serotonin, norepinephrine, and dopamine in the brain, it is a logical contributor to the pathophysiology of depression.22,23 Meyer et al22 studied 17 healthy individuals and 17 individuals with MDD to determine if MAO-A levels in the brain are elevated during episodes of untreated depression
References Heffernan, M., Summers, R.J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W.J., & Ng, F.M
[DOI] [PubMed] [Google Scholar] MacFarlane 2011 MacFarlane AJ, GreeneFinestone LS, Shi Y
The exploitation of the structure of a reference peptide molecule to obtain a non-peptidic mimic is described for each of them
