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A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia

Multi-dose vials are punctured multiple times, and each puncture is an opportunity for microbial introduction
Chemotherapy-induced mucosal injury is also influenced by pro-inflammatory cytokines such as TNF, interferon- (IFN ), interleukin 1 (IL-1), and IL-6 [76, 77]

Exp Hematol Oncol 5(1):27 Dinkova-Kostova AT, Fahey JW, Wade KL, Jenkins SN, Shapiro TA, Fuchs EJ et al (2007) Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts

H., Gladwin M
