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Such treatment has resulted in a substantial reduction in the accumulation of amyloid- (A) plaque and an improvement in cognitive performances (99, 100)
Protein glycosylation are either N-linked or O-linked
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Various study on IGF-1R, IGF-1 and IGF-2 expressions reported findings usable for useful patient stratification in future trials with inhibitors of the IGF-1R signaling pathway, to sort out those that may benefit the most from anti-IGF-1R therapies, limiting exposure of other patients to these agents (62, 63)
