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Second, the doses are small because the target is a high-affinity intracellular enzyme, not a receptor that needs saturating with milligrams of drug

This is true for many situations: when you meet your future spouse, or when you are in a job interview, or your first appearance as a player in a premier league game

Expected duration of vitamin B12 deficiency With proper treatment, symptoms of vitamin B 12 deficiency begin to improve within a few days

For others, like chronic celiac or Crohns disease, you may need B12 injections throughout your life

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