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Nat Rev Mol Cell Biol 12, 709-21 Guillet, V

Conjugated and Unconjugated Drug and OA Transport by MRP1/ABCC1 Although initial investigations of MRP1 mostly focused on its role in cancer multidrug resistance, the discovery that it could transport both conjugated and unconjugated OAs greatly broadened its pharmacological and physiological relevance (Fig

10.1016/bs.vh.2022.11.001

The colonization of intestinal microbiota is far from complete at birth and is influenced by various environmental factors, including breastfeeding duration (189)

Crucially, early empirical broad-spectrum antibiotics are mandatory to mitigate the imminent risk of bacterial translocation and sepsis[176-178]
