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However, the overall results depend on the consistency of treatment and maintaining healthy lifestyle habits

Although its not known for certain, many researchers think it was an administrative or religious center, perhaps a refuge for the last Inca, Manco Inca, during the resistance against the Spaniards

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Cochrane review (2025): A review of 17 clinical trials representing 2,069 patients with MASLD found that supplementing with silymarin alone versus placebo may be effective in reducing certain liver enzymes (ALT, GGT), though the authors were "very uncertain" of this effect due to limited sample sizes and suboptimal study design