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In particular, the antioxidative and anti-inflammatory properties of these PUFA may help protect neurons, promote synaptic plasticity, and limit cellular death

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The basic toxicology and pathologic manifestations of valproate sodium in neonatal (4-day old) and juvenile (14-day old) rats are similar to those seen in young adult rats

This intricate nexus, predominantly involving peripherally activated immune cells, notably circulating monocytes, and microglia, along with its repercussions on signaling pathways like serotonin, dopamine, and corticotropin-releasing hormone, with the latters implications on the hypothalamus-pituitaryadrenal axis, initiates sickness behaviors, including fatigue (4, 8)

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