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These secretagogues are distinct from the growth hormone-releasing (GHR) or Growth Hormone Releasing Peptide (GHRP) in that they share no sequence relation and derive their function through action at a completely different receptor, the ghrelin receptor

demonstrated that combined GHRH + GHRP administration produced 2 to 3 times more GH release than either compound individually in healthy subjects (Anderson et al., J Clin Endocrinol Metab 2001)

Concentration limitations

Electron microscopic localization of lacZ expression in the proximal convoluted tubular cells of the kidney in transgenic mice carrying chimeric erythropoietin/lacZ gene constructs

[DOI] [PubMed] [Google Scholar] 87.Stabile LP, He G, Lui VW, Thomas S, Henry C, Gubish CT, et al