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Nattokinase decreases plasma levels of fibrinogen, factor VII, and factor VIII in human subjects

10.1113/JP280572 J

Three metabolic pathways are known: - Glucuronidation (about 40% of the metabolism of the drug) - Sulfate conjugation (20-40%) - N-hydroxylation and rearrangement, then GSH conjugation (15%): the hepatic cytochrome P450 enzyme metabolizes the drug, forming a metabolite known as NAPQI (N-acetyl-p-benzo-quinone imine) that is irreversibly conjugated with sulphydryl group of glutathione

Let them air-dry for 5 seconds

10.1016/j.cell.2013.12.010 Cell 195 YeeC.YangW.HekimiS
