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Namun, pada pasien gagal ginjal kronis, terutama yang menjalani hemodialisis, mengalami defisiensi L-carnitine karena asupan yang berkurang atau bersihan yang meningkat selama dialisis, sehingga menimbulkan beberapa gejala seperti anemia, hipotensi berkaitan dengan dialisis, kerusakan otot jantung, dan malnutrisi.

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Interestingly, 3NT was found to correlate positively with several measures of cognitive function, development and behavior for the ASD/MD group, but not the ASD/NoMD group, such that higher 3NT concentrations were associated with more favourable adaptive behaviour, language and ASD-related behavior

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