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doi: 10.1007/s11010-022-04492-3

Author contributions Y-OK designed the experiments and wrote the manuscript

Now, in this study, a novel role for AMPK mediating mitochondrial fragmentation via the phosphorylation of the mitochondrial fission factor (MFF) is described

32666 Thoracoscopy with lobectomy (removal of a lobe)

Unresolved questions and future directions Currently, despite promising prospects in preclinical models, targeting glutamine metabolism faces challenges in clinical trials due to inherent heterogeneity in glutamine metabolism within tumor cells and immune cells, as well as its complex impact on immune responses