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The 2024 NICE Guideline NG239 from the United Kingdoms National Institute for Health and Care Excellence similarly distinguishes between patients who can be managed with oral therapy and those who require intramuscular treatment

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[11] [12] In his teens, Holland briefly attended carpentry school in Cardiff, Wales
Liver disease, kidney disease, and various cancers can all raise B12 levels, which is why studies finding associations between high B12 and poor health outcomes are generally measuring the effect of these diseases on B12 levels, not vice-versa

Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module
