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These observations allowed postulating that intracellular redox state of the thiol pool, which strongly depends on GSH level, can drive autophagic response at multiple levels (Filomeni et al., 2010)

The gene TRIM59 , where cg07553761 is located, was associated with cell death signaling in the familial form of Alzheimers disease when hypermethylated 29

Using a combination of state-of-the-art multi-omics technologies, we recently identified the presence and activity of oxidant stress-sensitive fatty acid desaturases (especially FADS2) in mature RBCs [104]

In a rodent model subjected to chronic alcohol exposure, NAC was found to upregulate Nrf2, resulting in a decrease in hippocampal oxidative stress, as evidenced by a lower GSSG/GSH ratio [44]

The number of TH-positive cells in the MH group was comparable to the NC group, significantly higher than in the ROT group ( P = 1.0 \(\times 10\) 4 )