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A meta-analysis found an association in myocardial infarction patients between supplementation with L-carnitine and a lower risk of ventricular arrhythmias.

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Current models for studying microbial TMA production have numerous weaknesses including the cost and length of human studies, differences in TMA(O) metabolism in animal models and the risk of failing to replicate multi-enzyme/multi-strain pathways when using isolated bacterial strains

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