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AOD-9604 Safety Profile and Potential Side Effects Safety data from over 900 clinical trial participants provides comprehensive information about AOD-9604s tolerability, side effect profile, and important contraindications

Results showed that the ingredient significantly increased NAD+ levels in senescent fibroblasts, activated the SIRT1 signaling pathway, reduced the expression of senescence-associated -galactosidase (SA--gal), decreased intracellular reactive oxygen species accumulation, and promoted collagen synthesis

Additionally, Clark points out that gastrointestinal conditions, such as celiac disease, Crohns disease and ulcerative colitis, can impair absorption in the small intestines, contributing to low B12 levels

That is a very different statement from they do nothing. It means: The mechanistic rationale is real

Older adults are at a higher risk for B12 deficiency for a number of reasons: Digestive issues that interfere with absorption Reduced food intake Dental issues that discourage meat consumption Disturbances to the gut biome Excess alcohol consumption Reduced stomach acid production that lowers absorption Reduced consumption and absorption of B12 can lead to neurological disorders, cognitive impairment and a number of other issues that accelerate aging and reduce overall quality of life