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The induction of ferroptosis by impairing STAT3/Nrf2/GPx4 signaling enhances the sensitivity of osteosarcoma cells to cisplatin

The synthesis of these -glutamyl peptides by -GCS and GS appears more likely to occur when cells are under pathological conditions that feature a Cys deficiency (Figure 7)

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Autoimmune Disorders: Autoimmune disorders, such as autoimmune hepatitis and primary biliary cirrhosis, can cause inflammation and damage to the liver, resulting in high liver enzyme levels

Phosphorylation of the C terminus of Fos protein is required for transcriptional transrepression of the c-fos promoter