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All patients performed the number connection test A and B using neuropsychological tests 21

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Notable proteins decreased in APOE4 iHLCs included APP, ferritin heavy chain 1 (FTH1), insulin-like growth factor binding protein 7 (IGFBP7), SPARC related modular calcium binding 2 (SMOC2), and metalloproteinase inhibitor 3 (TIMP3)

[PubMed] [Google Scholar] 17.Gibson N, Baker D, Sharples A, Braakhuis A