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Massive accumulation of -amyloid plaques is often seen in the brains of patients with AD, which induces increased expression of Piezo1

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Simple explanation: Being dehydrated can make someone look and feel less coordinated for reasons that have nothing to do with how much alcohol is actually in their blood which means dehydration could plausibly affect how someone performs on a balance-based sobriety test, even if it barely moved their real BAC